The iron form of methane mono-oxygenase and its mode of action.
نویسندگان
چکیده
Doller, D. and Hu, B. (1992) Tetrahedron Lett. 33, 27 Barton, D. H. R., Bevicre, S. D., Chavasiri, W., 69 5473-5476 28 Leising, R. A., Kim, J., Perez, M. A. and Que, Jr., L. (1993) J. Am. Chem. SOC. 115,9524-9530 29 Menage, S., Vincent, J.-M., Lambeaux, C., Chottard, G., Grand, A. and Fontecave, M. (1993) Inorg. Chem. 32,4766-4773 30 Menage, S., Vincent, J.-M., Lambeaux, C. and Fontecave, M. (1994) Tetrahedron Lett. 35,
منابع مشابه
Reactivity of methane mono-oxygenase, insights from quantum mechanic studies on synthetic iron model complexes
Methane mono-oxygenase (MMO) and deoxyhemerythrin (DHr) are examples of di-iron enzymes that catalyze the dissociative and non-dissociative binding of molecular oxygen. To mimic the MMO active site with a finite cluster, we chose to study the binuclear heptapodate coordinated iron(III)-complexes of N,N,N′,N′-tetrakis(2-benzimidazolylmethyl)-2-hydroxy-1,3diamino-propane (HPTB) and N,N,N′,N′-tetr...
متن کاملMechanistic pathways in soluble methane mono-oxygenase.
is ;I three component enzyme (hydroxylase, reductase ;ind regulator protein) that catalyses the NAI)(P)l I,and 0,-driven oxidation of methane to methanol. 'I'he hydroxylase is the site of methane ;ictivation, and has been shown t o contain a hinuclear hydroxyl-bridged iron species that is structurally similar to the hinuclear centre in the K2 subunit of ribonucleotide reductase [ 1 1. Substrate...
متن کاملSoluble Methane Mono-oxygenase of Methylococcus capsulatus (Bath)
1. Methane mono-oxygenase of Methylococcus capsulatus (Bath) catalyses the oxidation of various substituted methane derivatives including methanol. 2. It is a very non-specific oxygenase and, in some of its catalytic properties, apparently resembles the analogous enzyme from Methylomonas methanica but differs from those found in Methylosinus trichosporium and Methylomonas albus. 3. CO is oxidiz...
متن کاملThe metal centres of particulate methane mono-oxygenase.
pMMO (particulate methane mono-oxygenase) is an integral membrane metalloenzyme that catalyses the oxidation of methane to methanol. The pMMO metal active site has not been identified, precluding detailed investigation of the reaction mechanism. Models for the metal centres proposed by various research groups have evolved as crystallographic and spectroscopic data have become available. The pre...
متن کاملIdentification of the ferroxidase centre of Escherichia coli bacterioferritin.
The bacterioferritin (BFR) of Escherichia coli takes up iron in the ferrous form and stores it within its central cavity as a hydrated ferric oxide mineral. The mechanism by which oxidation of iron (II) occurs in BFR is largely unknown, but previous studies indicated that there is ferroxidase activity associated with a site capable of forming a dinuclear-iron centre within each subunit [Le Brun...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 25 1 شماره
صفحات -
تاریخ انتشار 1997